Professor Andrew Martin of Cambridge University solves the world's greatest mathematical riddle. Then he disappears. When he is found walking naked along the motorway, Professor Martin seems different. Besides the lack of clothes, he now finds normal life pointless. His loving wife and teenage son seem repulsive to him. In fact, he hates everyone on the planet. Everyone, that is, except Newton. And he's a dog. Can a bit of Debussy and Emily Dickinson keep him from murder?